AMP Comments and Update - AK's MSers - Monday, 19-June-2000 AMP = Adenosine Monophosphate. First recorded use of AMP on MS is late '40s early '50s by two MDs who treated their own MS (and their MS patients) with AMP. AMP is a natural substance of the human body, it converts to ATP which are neurotransmitters (NT). Drs Shearer and Bjork found that AMP, used over time, will stop new exacerbations from happening. Besides bladder, balance and other improvements, it also causes increased muscle strenght and duration, this is very noticable from the start of use. Individuals began experiencing lasting remissions between a period of time ranging from a matter of months to a few years after starting AMP. AMP should be used along with vit. B12. Besides producing NTs, AMP & B12 combined produce a number of coenzymes and increase the remyelination process. Drs Shearer, Bjork and the physicians currently prescibing it for other MSers I know, are going with the IM injectable AMP & B12. It comes in an oral form, but that form is not recommended for MS, as MSers don't absorb well intestinally. GoodShape is experimenting with a skin application of AMP, perhaps soon he will be able to let us know if that delivery system improves Polly's MS symptoms. I don't think you need an Rx for the oral tables of AMP, but you do need one for the injectable. The best read on AMP is a book by Dr. Shearer. You can get a copy from the medical researcher (Maury) mention in "Posts to Remember" at the top of the board. I forgot to mention - Yes, it can be taken along with histamine and caffeine. The MSers in AK that are on AMP are doing just histamine patchless, however. I am hoping that I hear from my Dr. today as to whether I can add LDN to my use of histamine and AMP. I started doing injectable histamine last August. I added AMP a little over 3 mos. ago. I see a huge imporvement having added AMP. I have always been a coffee drinker, but caffeine use pales in comparison to the effects I see on AMP. I would like to add LDN as extr measure against new exacerbations. I am impressed with what I've read here from others on LDN More Comments - AK'sMSers - Monday, September-11-2000 Some of the posters here are doing a skin app of AMP. The studies on using AMP (studies available on under "posts to remember")say that in order to get benefit, AMP must be injected IM. There is a biological change that has to occur in the AMP once it is in contact with muscle that makes it effective in significantly increasing muscle strength and duration, bladder control, eyesight, stoping spacticity, and more. There are quite a few of us who are doing IM AMP along with B12 and B complex. Although IM method is not anything anyone rushes to do...the benefits far outweigh the shot itself, and is therefore very worth the trouble. If you decide to use AMP IM, make sure it is PH neurtalized--the non PH balanced stings-up-a-storm. One of our AK group (who does it IM) ran out of his AMP for about 10 days. He called me after he got back on it and said he will never allow himself to run out of it again. He took a huge dive in his leg strength and ability to walk while off it. I do IM AMP, 1cc daily. Wow, I can work out longer and don't get muscle fatigue. I have done AMP this way for about 5 months or more. Perhaps someone who is using it as a skin app. can tell you the differences they see.   **************************************************************************************** Three Methods MS Experimenters use for preparing and applying AMP according to GoodShape - Nov 2000: Supplies needed: 1) AMP (Adenosine-5'-monophosphate,Free Acid CAS 61-19-8), 2) A 3ml Dropper Bottle (Binaca Blaster or the one supplied in GoodShape's free sample) and 3) Kodak 35mm film cannister (if making AMP Cream). Method 1) Duplicate the same method described on GoodShape's Homepage for making Histamine Drops. Use the Dropper Bottle Cap as a measuring cup and add AMP completely to the first ledge in the bottom of the cap. This will almost equal 150mg of AMP. Mix it with 3ml of water in the Dropper Bottle just like making Histamine. This will yield approximately 60 big drops of 2.5mg AMP each. It will not disolve as well as Histamine so shake the Dropper Bottle before each application. Apply on top of Histamine application before Caffeine Cream application or on another prepped site followed by Cream. Some Experimenters only apply AMP in the AM if it effects their sleep. Method 2) Put 10ml (2 teaspoons) of a Base Cream (Vanicream or other) in a film cannister - about 1/3 full. Add 150mg of AMP as measured in Method 1 and stir until completely mixed. This will yield 50 to 60 applications of 2.5mg AMP at a liitle less than 0.2 ml (pea size) each. Apply before or after Caffeine Cream application when doing Histamine Drops & Caffeine Cream Treatments. Method 3) Put 10ml (2 teaspoons) of GoodShape's Caffeine Cream in a film cannister - about 1/3full. Add 150mg of Amp as measured in Method 1 and stir until completely mixed. This will add approximately 2.5mg of AMP to each dose of Caffeine Cream. Use this Cream in the same manner as you previously used the Caffeine Cream. Or use this AMP/Caffeine Cream in the AM and Original Caffeine Cream in the PM.